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Charm II


The Charm II system provides comprehensive food safety testing for multiple food matrices. The Charm II 6600 is used to test for a wide range of residues in milk and honey. The Charm 7600 is used for milk, egg, fish, grain, honey, serum, tissue, urine, and water testing.


With the Charm II system, laboratories can test for the following residues:


  • Antibiotics, including aminoglycosides, amphenicols, beta-lactams, macrolides, novobiocin, sulfonamides, and tetracyclines
  • Aflatoxin B1 in grain and aflatoxin M1 in milk
  • Pesticides, using the Charm CideLite test
  • Alkaline phosphatase (a biomarker for incomplete pasteurization), using the Charm PasLite test
  • ATP (for hygiene), using the PocketSwab Plus and other Charm swabs.


Charm II is the choice of food industry laboratories and regulators around the world because of the wide variety of tests offered and the system’s versatility, reliability, and accuracy.


Many labs use the Charm II to screen food products for domestic monitoring or international trade. Other labs use the Charm II in conjunction with HPLC to detect and identify specific antimicrobial drugs and their metabolites.



  • Milk tests detect sulfonamides at US safe levels, EU MRL, or CODEX MRL
  • The US milk assay is recognized by the NCIMS (National Conference on Interstate Milk Shippers) when the competitive assay is used.
  • Tissue test detects sulfonamides at US safe levels and EU and CODEX MRLs
  • Grain and honey tests are available
  • Tests take 10-15 minutes after any needed extraction
  • One platform tests multiple sample types
  • Tests designed for use by veterinary, laboratory, field, and regulatory personnel



Regulatory Info

  • The Charm II SULFA test for milk detects four sulfonamide drugs at or below US safe level. The Charm II SULFA test is recognized by the National Conference on Interstate Milk Shipments (NCIMS) when the competitive assay is used.
  • The Charm II SULFAMRL test for milk detects sulfonamides at the EU MRL of 100 ppb total sulfonamides in cow milk. It also detects sulfamethazine (sulfadimidine) at the CODEX MRL of 25 ppb with a modified procedure. Central Reference Laboratory (CRL) guidelines available upon request.

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